Dataset Information
Three new sesquiterpenes from roots of Curcuma longa.
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ABSTRACT: Objective
To study the chemical constituents from the roots of Curcuma longa.Methods
The structures of the compounds were elucidated based on extensive spectral analysis, including 1D and 2D NMR, MS, UV, and CD analysis.Results
Two new sesquiterpene compounds (1S,2R,5R,7S,8R)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (1), (1R,2R,5R,7S,8R)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (2), and a new natural product 6-(4-Hydroxymethylphenyl)-2-methyl-hept-2-ene-4-one (3) together with three known compounds ar-turmerone (4), 2-methyl-6-(4-hydroxyphenyl-3-methyl)-2-hepten-4-one (5) and 2-methyl-6-(4-hydroxyphenyl)-2-hepten-4-one (6) were isolated from C. longa root extract with 95% ethanol.Conclusion
In the study, three new compounds were isolated from C. longa, and their absolute configurations were determined.
SUBMITTER: Zhang J
PROVIDER: S-EPMC10394330 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Publications
Three new sesquiterpenes from roots of <i>Curcuma longa</i>.
Chinese herbal medicines 20230522 3
<h4>Objective</h4>To study the chemical constituents from the roots of <i>Curcuma longa</i>.<h4>Methods</h4>The structures of the compounds were elucidated based on extensive spectral analysis, including 1D and 2D NMR, MS, UV, and CD analysis.<h4>Results</h4>Two new sesquiterpene compounds (1<i>S</i>,2<i>R</i>,5<i>R</i>,7<i>S</i>,8<i>R</i>)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (<b>1</b>), (1<i>R</i>,2<i>R</i>,5<i>R</i>,7<i>S</i>,8<i>R</i>)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (<b ...[more]
