Outcomes in infants with unprovoked venous thromboembolism: A retrospective cohort study.

ABSTRACT:

Background

Although children aged <1 year have a relatively high rate of venous thromboembolism (VTE) compared to older children, most have additional prothrombotic risk factors. Unprovoked VTE is rare, and little is known about this population, particularly the risk of recurrent VTE.

Objectives

We aimed to determine the rate of recurrent VTE in infants with prior unprovoked VTE and evaluate long-term, end-organ outcomes for infants with renal and intracranial vein thrombosis.

Methods

Infants <1 year of age with an unprovoked VTE between 2003 and 2021 at a single institution were included. Time to recurrent event and anticoagulation duration were summarized using the Kaplan-Meier estimator. Neurologic outcomes were summarized with the pediatric stroke outcome measure

SUBMITTER: Whitworth H 

PROVIDER: S-EPMC10394551 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature