Association between antenatal corticosteroids and risk of serious infection in children: nationwide cohort study.

ABSTRACT:

Objective

To investigate the associations between exposure to antenatal corticosteroids and serious infection in children during the first three, six, and 12 months of life.

Design

Nationwide cohort study.

Setting

National Health Insurance Research Database, Birth Reporting Database, and Maternal and Child Health Database, 1 January 2008 to 31 December 2019, to identify all pregnant individuals and their offspring in Taiwan.

Participants

1 960 545 pairs of pregnant individuals and their singleton offspring. 45 232 children were exposed and 1 915 313 were not exposed to antenatal corticosteroids.

Main outcome measures

Incidence rates were estimated for overall serious infection, sepsis, pneumonia, acute gastroenteritis, pyelonephritis, meningitis or encep

SUBMITTER: Yao TC 

PROVIDER: S-EPMC10394679 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature