MRI assessment of rectal cancer response to neoadjuvant therapy: a multireader study.

ABSTRACT:

Objectives

A watch and wait strategy with the goal of organ preservation is an emerging treatment paradigm for rectal cancer following neoadjuvant treatment. However, the selection of appropriate patients remains a challenge. Most previous efforts to measure the accuracy of MRI in assessing rectal cancer response used a small number of radiologists and did not report variability among them.

Methods

Twelve radiologists from 8 institutions assessed baseline and restaging MRI scans of 39 patients. The participating radiologists were asked to assess MRI features and to categorize the overall response as complete or incomplete. The reference standard was pathological complete response or a sustained clinical response for > 2 years.

Results

We measured the accuracy and desc

SUBMITTER: Yuval JB 

PROVIDER: S-EPMC10394731 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature