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Association between serum Klotho concentration and hypertension in postmenopausal women, a cross-sectional study from NHANES 2013-2016.


ABSTRACT:

Background

The objective of this study was to examine the correlation between serum Klotho protein concentration and postmenopausal hypertension.

Methods

A cross-sectional study design was used, in which 1713 postmenopausal women who participated in the National Health and Nutrition Examination Survey (NHANES) 2013-2016 were included. Multivariate logistic regression models were applied to assess the association between serum Klotho concentration and postmenopausal hypertension.

Results

A weighted analysis was executed, revealing a noteworthy hypertension prevalence rate of 53.44% among the study participants. Participants with lower quartile of serum Klotho concentration had a higher prevalence of hypertension than those in higher quartiles (Q1:62.29% vs. Q2: 48.52%

SUBMITTER: Yu J 

PROVIDER: S-EPMC10394796 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature