Incidence of hospital-acquired acute kidney injury and trajectories of glomerular filtration rate in older adults.

ABSTRACT:

Background

In older adults, epidemiological data on incidence rates (IR) of hospital-acquired acute kidney injury (AKI) are scarce. Also, little is known about trajectories of kidney function before hospitalization with AKI.

Methods

We used data from biennial face-to-face study visits from the prospective Berlin Initiative Study (BIS) including community-dwelling participants aged 70+ with repeat estimated glomerular filtration rate (eGFR) based on serum creatinine and cystatin C. Primary outcome was first incident of hospital-acquired AKI assessed through linked insurance claims data. In a nested case-control study, kidney function decline prior to hospitalization with and without AKI was investigated using eGFR trajectories estimated with mixed-effects models adjusted for

SUBMITTER: Ebert N 

PROVIDER: S-EPMC10394866 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature