Progress and prospects of gene therapy in ophthalmology from 2000 to 2022: A bibliometric analysis.

ABSTRACT:

Background

Gene therapy is a treatment approach at the genetic level, which brings great advances in many diseases and develops rapidly in recent years. Currently, its mechanism of action is mainly through the replacement of missing or defective genes, or the reduction of harmful gene products. However, the application of gene therapy in ophthalmology remains limited.

Methods

A total of 1143 articles and reviews published in the field of ocular gene therapies were found in the Web of Science Core Collection database and used for the bibliometric analysis. CiteSpace was mainly applied to the network analysis of countries, institutions, keywords, and dual-map overlay of journals. The visual analysis of authors, journals, and references was used by VOSviewer. The geographical d

SUBMITTER: Li B 

PROVIDER: S-EPMC10395483 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature