Proton Pump Inhibitor Use and Cognitive Function in the Boston Puerto Rican Health Study.

ABSTRACT:

Background

There is a lack of consensus among studies on the association between proton pump inhibitor (PPI) use and cognitive impairment. This association is not well studied among minority populations, including among Puerto Ricans. Therefore, we sought to examine this association among Boston-area Puerto Ricans.

Methods

The Boston Puerto Rican Health Study is an ongoing longitudinal cohort that enrolled 1499 Boston-area Puerto Rican adults, aged 45-75 years at baseline. Complete outcome and exposure data was available for 1290 baseline participants. Covariate-adjusted linear regression and linear mixed effects models were used to examine the association between PPI use, and global cognition, executive function, and memory cross-sectionally and longitudinally over ~12.7 ye

SUBMITTER: Dinesh D 

PROVIDER: S-EPMC10395560 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature