Intrinsically fluorescent and quercetin loaded highly crosslinked polyphosphazene nanospheres: synthesis, characterization and fluorescence properties.

ABSTRACT: Highly crosslinked, inorganic-organic hybrid and intrinsically fluorescent polyphosphazene nanospheres bearing hydroxyl groups on the surface are facilely generated via a one-pot polycondensation of octachlorocyclotetraphosphazene, fluorescein and quercetin. The resulting nanospheres were characterised by scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDX), Fourier transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), X-ray diffraction analysis (XRD) and ultraviolet-visible spectroscopy (UV-vis) techniques. The average diameter of the nanospheres was determined as 379 nm. Also, quercetin which is both a monomer and an anticancer drug was loaded to the nanospheres as 446 mg g^-1. The obtained nanospheres possess outstanding dispe

SUBMITTER: Metinoglu Orum S 

PROVIDER: S-EPMC10395785 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature