The development of blood protein profiles in extremely preterm infants follows a stereotypic evolution pattern.

ABSTRACT:

Background

Preterm birth is the leading cause of neonatal mortality and morbidity. Early diagnosis and interventions are critical to improving the clinical outcomes of extremely premature infants. Blood protein profiling during the first months of life in preterm infants can shed light on the role of early extrauterine development and provide an increased understanding of maturation after extremely preterm birth and the underlying mechanisms of prematurity-related disorders.

Methods

We have investigated the blood protein profiles during the first months of life in preterm infants on the role of early extrauterine development. The blood protein levels were analyzed using next generation blood profiling on 1335 serum samples, collected longitudinally at nine time points from b

SUBMITTER: Zhong W 

PROVIDER: S-EPMC10397184 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature