Risks of fatal opioid overdose during the first year following nonfatal overdose.

ABSTRACT:

Background

Little is known about risk factors for repeated opioid overdose and fatal opioid overdose in the first year following nonfatal opioid overdose.

Methods

We identified a national retrospective longitudinal cohort of patients aged 18-64 years in the Medicaid program who received a clinical diagnosis of nonfatal opioid overdose. Repeated overdoses and fatal opioid overdoses were measured with the Medicaid record and the National Death Index. Rates of repeat overdose per 1000 person-years and fatal overdose per 100,000 person-years were determined. Hazard ratios of repeated opioid overdose and fatal opioid overdose were estimated by Cox proportional hazards.

Results

Nearly two-thirds (64.8%) of the patients with nonfatal overdoses (total n = 75,556) had filled o

SUBMITTER: Olfson M 

PROVIDER: S-EPMC10398609 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature