Toward the Detection Limit of Electrochemistry: Studying Anodic Processes with a Fluorogenic Reporting Reaction.

ABSTRACT: Recently, shot noise has been shown to be an inherent part of all charge-transfer processes, leading to a practical limit of quantification of 2100 electrons (≈0.34 fC) [ Curr. Opin. Electrochem. 2020, 22, 170-177]. Attainable limits of quantification are made much larger by greater background currents and insufficient instrumentation, which restricts progress in sensing and single-entity applications. This limitation can be overcome by converting electrochemical charges into photons, which can be detected with much greater sensitivity, even down to a single-photon level. In this work, we demonstrate the use of fluorescence, induced through a closed bipolar setup, to monitor charge-transfer processes below the detection limit of electrochemical workstations. During this process, the

SUBMITTER: Linfield S 

PROVIDER: S-EPMC10398625 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature