Tracking of serum lipids in healthy children on a year-to-year basis.

ABSTRACT:

Objectives

To assess the stability of lipid profiles throughout childhood and evaluate their onset and dynamic.

Materials and methods

Lipid markers were longitudinally measured in more than 1300 healthy children from the LIFE Child study (Germany) and categorized into normal, at-risk, or adverse. Year-to-year intra-person persistence of the categories during follow-ups was examined and Pearson's correlation coefficient was calculated.

Results

We found strong positive correlations for TC, LDL-C and ApoB (r > 0.75, p < 0.001) from the age of four years. Correlations were lowest during the first two years of life. Most children with normal levels also had normal levels the following year. Children with at-risk levels showed a tendency towards normal levels at the follow-

SUBMITTER: Maidowski L 

PROVIDER: S-EPMC10398926 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature