Characterizing Fast and Slow Progressors in Anterior Circulation Large Vessel Occlusion Strokes.

ABSTRACT:

Background and purpose

Infarct growth rate (IGR) in acute ischemic stroke is highly variable. We sought to evaluate impact of symptom-reperfusion time on outcomes in patients undergoing mechanical thrombectomy (MT).

Methods

A prospectively maintained database from January,2012-August,2020 was reviewed. All patients with isolated MCA-M1 occlusion who achieved complete reperfusion(mTICI2C-3), had a witnessed symptom onset and follow-up MRI were included. IGR was calculated as final infarct volume (FIV)(ml)/symptom onset to reperfusion time(hours) and was dichotomized according to the median value into slow-(SP) versus fast-progressors (FP). The primary analysis aimed to evaluate the impact of symptom-reperfusion time on 90-day mRS in SP and FP. Secondary analysis was performed

SUBMITTER: Mohammaden MH 

PROVIDER: S-EPMC10399496 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature