Comparison of Quality of Life and Psychiatric Symptoms Between Patients With Diarrhea-Predominant Irritable Bowel Syndrome and Those With Constipation-Predominant Irritable Bowel Syndrome.
Comparison of Quality of Life and Psychiatric Symptoms Between Patients With Diarrhea-Predominant Irritable Bowel Syndrome and Those With Constipation-Predominant Irritable Bowel Syndrome.
Project description:We used fresh ileum tissue samples and performed single-cell RNA sequencing with the DNBelab C4 platform to investigate the mechanisms by which OEA treatment affects IBS-D-related symptoms in TNBS-treated mice. This approach enabled us to analyze cell-type-specific transcriptomic changes and to identify key cellular responses following OEA intervention in the context of TNBS-induced IBS-D symptoms