Continuous, long-term crawling behavior characterized by a robotic transport system.

ABSTRACT: Detailed descriptions of behavior provide critical insight into the structure and function of nervous systems. In Drosophila larvae and many other systems, short behavioral experiments have been successful in characterizing rapid responses to a range of stimuli at the population level. However, the lack of long-term continuous observation makes it difficult to dissect comprehensive behavioral dynamics of individual animals and how behavior (and therefore the nervous system) develops over time. To allow for long-term continuous observations in individual fly larvae, we have engineered a robotic instrument that automatically tracks and transports larvae throughout an arena. The flexibility and reliability of its design enables controlled stimulus delivery and continuous measurement ov

SUBMITTER: Yu J 

PROVIDER: S-EPMC10400072 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature