Large-scale neural dynamics in a shared low-dimensional state space reflect cognitive and attentional dynamics.

ABSTRACT: Cognition and attention arise from the adaptive coordination of neural systems in response to external and internal demands. The low-dimensional latent subspace that underlies large-scale neural dynamics and the relationships of these dynamics to cognitive and attentional states, however, are unknown. We conducted functional magnetic resonance imaging as human participants performed attention tasks, watched comedy sitcom episodes and an educational documentary, and rested. Whole-brain dynamics traversed a common set of latent states that spanned canonical gradients of functional brain organization, with global desynchronization among functional networks modulating state transitions. Neural state dynamics were synchronized across people during engaging movie watching and aligned to narrativ

SUBMITTER: Song H 

PROVIDER: S-EPMC10400080 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature