Effect of vaginal microbiota on pregnancy outcomes of women from Northern China who conceived after IVF.

ABSTRACT:

Objective

This study aimed to investigate the correlation between vaginal microbiota and pregnancy outcomes of women who achieved pregnancy via in vitro fertilization (IVF) in Northern China, and to determine a biomarker for evaluation of the risk of preterm births in these women.

Methods

In total, 19 women from Northern China women who conceived after IVF and 6 women who conceived naturally were recruited in this study. The vaginal samples of the healthy participants were collected throughout pregnancy, that is, during the first, second, and third trimesters. The V3-V4 region of 16S rRNA was used to analyze the vaginal microbiome, and the bioinformatic analysis was performed using QIIME Alpha and Beta diversity analysis.

Results

Either IVF group or Natural con

SUBMITTER: Tong Y 

PROVIDER: S-EPMC10400330 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature