Increased risk of dementia among people with a history of fractures: a systematic review and meta-analysis of population-based studies.

ABSTRACT:

Background

Emerging evidence suggests that there may be an association between a history of fractures and dementia risk, but the epidemiological findings are inconsistent. We, therefore, conducted a meta-analysis to systematically assess the risk of dementia among people with a history of fractures.

Methods

We comprehensively searched four electronic databases (PubMed, Web of Science, Embase, and Cochrane Library) for relevant literature published from inception to 10 January 2023. Longitudinal observational studies that investigated the association between any type of fracture occurrence and the subsequent risk of dementia were included for qualitative and quantitative analysis. Risk estimates were pooled using fixed-effects or random-effects models according to the level o

SUBMITTER: Su L 

PROVIDER: S-EPMC10400716 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature