Association of retinal nerve layers thickness and brain imaging in healthy young subjects from the i-Share-Bordeaux study.

ABSTRACT: Given the anatomical and functional similarities between the retina and the brain, the retina could be a "window" for viewing brain structures. We investigated the association between retinal nerve fiber layers (peripapillary retinal nerve fiber layer, ppRNFL; macular ganglion cell-inner plexiform layer, GC-IPL; and macular ganglion cell complex, GCC), and brain magnetic resonance imaging (MRI) parameters in young health adults. We included 857 students (mean age: 23.3 years, 71.3% women) from the i-Share study. We used multivariate linear models to study the cross-sectional association of each retinal nerve layer thickness assessed by spectral-domain optical coherence tomography (SD-OCT) with structural (volumes and cortical thickness), and microstructural brain markers, assessed on MRI g

SUBMITTER: Lima Reboucas SC 

PROVIDER: S-EPMC10400793 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature