Sodium fluoride (Na¹⁸F) PET Response Criteria in Solid Tumors (NAFCIST): a framework for response assessment in bone tumors.

ABSTRACT: The current Response Evaluation Criteria in Solid Tumors for measuring tumor response in osteosarcoma may be sub-optimal, as even responsive bone tumors may show limited change in tumor diameters. This limits the use of traditional imaging assessment tools. Therefore, discerning osteosarcoma response to therapy on magnetic resonance imaging before surgery is often difficult, and it is typically evaluated after surgery by assessing the amount of necrosis in resected surgical specimens. To address these challenges, sodium fluoride (Na¹⁸F) positron emission tomography/computed tomography (PET/CT) scans can be utilized to better image bone response to therapy, as, fluoride is avidly taken up by bone. Na¹⁸F Response Criteria in Solid Tumors (NAFCIST) has been developed as

SUBMITTER: Kairemo K 

PROVIDER: S-EPMC10400850 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature