Mapping the evolution of regional brain network efficiency and its association with cognitive abilities during the first twenty-eight months of life.

ABSTRACT: Human brain undergoes rapid growth during the first few years of life. While previous research has employed graph theory to study early brain development, it has mostly focused on the topological attributes of the whole brain. However, examining regional graph-theory features may provide unique insights into the development of cognitive abilities. Utilizing a large and longitudinal rsfMRI dataset from the UNC/UMN Baby Connectome Project, we investigated the developmental trajectories of regional efficiency and evaluated the relationships between these changes and cognitive abilities using Mullen Scales of Early Learning during the first twenty-eight months of life. Our results revealed a complex and spatiotemporally heterogeneous development pattern of regional global and local efficiency

SUBMITTER: Jiang W 

PROVIDER: S-EPMC10400876 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature