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The characterization of toll-like receptor repertoire in Pinna nobilis after mass mortality events suggests adaptive introgression.


ABSTRACT: The fan mussel Pinna nobilis is currently on the brink of extinction due to a multifactorial disease mainly caused to the highly pathogenic parasite Haplosporidium pinnae, meaning that the selection pressure outweighs the adaptive potential of the species. Hopefully, rare individuals have been observed somehow resistant to the parasite, stretching the need to identify the traits underlying this better fitness. Among the candidate to explore at first intention are fast-evolving immune genes, of which toll-like receptor (TLR). In this study, we examined the genetic diversity at 14 TLR loci across P. nobilis, Pinna rudis and P. nobilis × P. rudis hybrid genomes, collected at four physically distant regions, that were found to be either resistant or se

SUBMITTER: Coupe S 

PROVIDER: S-EPMC10401143 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature