Serological survey to estimate SARS-CoV-2 infection and antibody seroprevalence at a large public university: A cross-sectional study.

ABSTRACT:

Objective

This study investigated the seroprevalence of SARS-CoV-2 antibodies among adults over 18 years.

Design

Prospective cohort study.

Settings

A large public university.

Participants

This study took volunteers over 5 days and recruited 1064 adult participants.

Primary outcome measures

Seroprevalence of SARS-CoV-2-specific antibodies due to previous exposure to SARS-CoV-2 and/or vaccination.

Results

The seroprevalence of the antireceptor binding domain (RBD) antibody was 90% by a lateral flow assay and 88% by a semiquantitative chemiluminescent immunoassay. The seroprevalence for antinucleocapsid was 20%. In addition, individuals with previous natural COVID-19 infection plus vaccination had higher anti-RBD antibody levels compared with those w

SUBMITTER: Hou CW 

PROVIDER: S-EPMC10401225 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature