Association between sarcopenia and frailty in elderly patients with chronic kidney disease.

ABSTRACT:

Background

Frailty and sarcopenia are prevalent in chronic kidney disease (CKD) populations and could increase the risk for adverse health outcomes. Few studies assess the correlation between frailty, sarcopenia and CKD in non-dialysis patients. Therefore, this study aimed to determine frailty-associated factors in elderly CKD stage I-IV patients, expected to early identify and intervene in the frailty of elderly CKD patients.

Methods

A total of 774 elderly CKD I-IV patients (>60 years of age) recruited from 29 clinical centers in China between March 2017 and September 2019 were included in this study. We established a Frailty Index (FI) model to evaluate frailty risk and verified the distributional property of FI in the study population. Sarcopenia was defined according to

SUBMITTER: Wang C 

PROVIDER: S-EPMC10401549 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature