Navigating the Complex Solid Form Landscape of the Quercetin Flavonoid Molecule.

ABSTRACT: Quercetin, a naturally occurring bioflavonoid substance widely used in the nutraceutical and food industries, exists in various solid forms that can have different physicochemical properties, thus impacting this compound's performance in various applications. In this work, we will clarify the complex solid-form landscape of this molecule. Two elusive isostructural solvates of quercetin were obtained from ethanol and methanol. The obtained crystals were characterized experimentally, but the crystallographic structure could not be solved due to their high instability. Nevertheless, the desolvated structure resulting from a high-temperature treatment (or prolonged storage at ambient conditions) of both these two labile crystals was characterized and solved via powder X-ray diffraction and sol

SUBMITTER: Klitou P 

PROVIDER: S-EPMC10401642 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature