The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques.

ABSTRACT: Each cortical area has a distinct pattern of anatomical connections within the thalamus, a central subcortical structure composed of functionally and structurally distinct nuclei. Previous studies have suggested that certain cortical areas may have more extensive anatomical connections that target multiple thalamic nuclei, which potentially allows them to modulate distributed information flow. However, there is a lack of quantitative investigations into anatomical connectivity patterns within the thalamus. Consequently, it remains unknown if cortical areas exhibit systematic differences in the extent of their anatomical connections within the thalamus. To address this knowledge gap, we used diffusion magnetic resonance imaging (dMRI) to perform brain-wide probabilistic tractography for 828

SUBMITTER: Howell AM 

PROVIDER: S-EPMC10401924 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature