Low dimensional criticality embedded in high dimensional awake brain dynamics.

ABSTRACT: Whether cortical neurons operate in a strongly or weakly correlated dynamical regime determines fundamental information processing capabilities and has fueled decades of debate. Here we offer a resolution of this debate; we show that two important dynamical regimes, typically considered incompatible, can coexist in the same local cortical circuit by separating them into two different subspaces. In awake mouse motor cortex, we find a low-dimensional subspace with large fluctuations consistent with criticality - a dynamical regime with moderate correlations and multi-scale information capacity and transmission. Orthogonal to this critical subspace, we find a high-dimensional subspace containing a desynchronized dynamical regime, which may optimize input discrimination. The critical subspace

SUBMITTER: Fontenele AJ 

PROVIDER: S-EPMC10401950 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature