Familial risk of postpartum psychosis.

ABSTRACT:

Objective

Postpartum psychosis, a mood disorder triggered by childbirth, is one of the most severe psychiatric conditions, with high risks of suicide and infanticide if untreated. While it is evident that genetic factors play a crucial role in disorder risk, the exact extent of their importance is yet to be determined.

Methods

This cohort study consisted of 1,648,759 women from the Swedish nationwide registers, of whom 2,514 (0.15%) experienced postpartum psychosis within three months of their first-ever childbirth. We estimated the relative recurrence risk of postpartum psychosis for female full siblings and cousins as a measure of familial, genetic, and environmental risk.

Results

Relative recurrence risk of postpartum psychosis in full siblings was 10.69 (95% CI=6.

SUBMITTER: Kepinska AP 

PROVIDER: S-EPMC10402213 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature