Identifying Obstructive Hypertrophic Cardiomyopathy from Nonobstructive Hypertrophic Cardiomyopathy: Development and Validation of a Model Based on Electrocardiogram Features.

ABSTRACT:

Background

The clinical presentation and prognosis of hypertrophic cardiomyopathy (HCM) are heterogeneous between nonobstructive HCM (HNCM) and obstructive HCM (HOCM). Electrocardiography (ECG) has been used as a screening tool for HCM. However, it is still unclear whether the features presented on ECG could be used for the initial classification of HOCM and HNCM.

Objective

We aimed to develop a pragmatic model based on common 12-lead ECG features for the initial identification of HOCM/HNCM.

Methods

Between April 1^st and September 30^th, 2020, 172 consecutive HCM patients from the International Cooperation Center for Hypertrophic Cardiomyopathy of Xijing Hospital were prospectively included in the training cohort. Between January 4^th an

SUBMITTER: Guo L 

PROVIDER: S-EPMC10402817 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature