Body composition and short-term mortality in patients critically ill with acute-on-chronic liver failure.

ABSTRACT:

Background & aims

Body composition is sex dependent and associated with an increased mortality risk in patients with cirrhosis. We evaluated whether it was also associated with short-term mortality in patients critically ill with acute-on-chronic liver failure (ACLF).

Patients and methods

We retrospectively included all patients with cirrhosis and ACLF hospitalised in the intensive care unit (ICU) of Lausanne University Hospital between 2010 and 2019 for whom an abdominal computed tomography (CT) scan performed ±7 days from admission was available. Patients from the ICU of Paul Brousse University Hospital admitted between 2017 and 2020 served as an external cohort. All body composition parameters at the third lumbar vertebral level (L3) were quantified using a deep learning-

SUBMITTER: Mangana Del Rio T 

PROVIDER: S-EPMC10403365 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature