Left atrium decompression devices across the spectrum of ejection fraction in heart failure: an updated systematic review and meta-regression analysis.

ABSTRACT:

Background

In patients affected by heart failure (HF) with reduced ejection fraction (HFrEF), pharmacological treatments have been proven to alleviate symptoms and improve prognosis, while no treatment other than sodium-glucose co-transporter-2 inhibitors have demonstrated significant effects in HF with preserved ejection fraction (HFpEF). Left atrium decompression devices (LADd) have been recently investigated as a new interventional approach in patients with HFpEF.

Objectives

To assess the efficacy of LADd on soft endpoints in HF patients across the spectrum of ejection fraction.

Methods

PubMed and Web of Science were searched without restrictions from inception to 28 May 2022 to identify valuable articles. The studies that met the inclusion criteria were analyzed.

SUBMITTER: Basile C 

PROVIDER: S-EPMC10403397 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature