An ultrasensitive NIR-IIa' fluorescence-based multiplex immunochromatographic strip test platform for antibiotic residues detection in milk samples.

ABSTRACT:

Introduction

Widely used in livestock breeding, residues of antibiotic drugs in milk have become a threat to food safety and human health. Current rapid detection technologies using colorimetric immunochromatographic strip tests (IST) lack the necessary sensitivity for on-site trace monitoring. Fluorescence-based detection in the near-infrared IIa' (NIR-IIa') region (1000 ∼ 1300 nm) has enormous potential due to greatly minimized auto-fluorescence and light scattering.

Objectives

The aim of this work is to develop an ultrasensitive IST platform using NIR-IIa' fluorescent nanoparticles as labels for multiplex antibiotic residues detection in milk.

Methods

NIR-IIa' fluorescent nanoparticles were assembled by encapsulating synthesized NIR-IIa' fluorophores into carboxyl

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC10403655 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature