Salivary microbiome profiles of oral cancer patients analyzed before and after treatment.

ABSTRACT:

Background

Treating oral squamous cell carcinoma (OSCC) introduces new ecological environments in the oral cavity. This is expected to cause changes in the oral microbiome. The purpose of this study was to gain new information on the salivary microbiome of OSCC patients in order to improve the aftercare of OSCC patients. The aims of this study were to investigate possible changes in the salivary microbiome profiles of OSCC patients before and after cancer treatment and to compare these changes with the profiles of healthy controls.

Patients and methods

Paraffin-stimulated whole saliva samples were collected, and the salivary flow rate was measured from 99 OSCC patients prior to surgical resection of the tumor and other adjuvant therapy. After treatment, 28 OSCC patients were

SUBMITTER: Makinen AI 

PROVIDER: S-EPMC10403937 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature