Impact of Interleukin-10 Promoter Region Polymorphisms on Recurrent Miscarriage: A Case-Control Approach.

ABSTRACT:

Background

Recurrent miscarriage (RM), defined as two or more consecutive miscarriages prior to the 20^th week of gestation is characterised by multifactorial aetiology. The prevalence of RM varies from 0.8% to 13.5% amongst women of reproductive age. The aetiological basis of RM has been traced to chromosomal, anatomic, hormonal and immunologic factors while half of the cases remain idiopathic.

Aims

This study aimed to investigate the association of interleukin-10 (IL-10) polymorphisms with RM amongst the Indian population.

Settings and design

The present study included a total of 414 individuals including RM women (n = 199) with two or more pregnancy losses and healthy women (n = 215) without any previous history of pregnancy loss were taken

SUBMITTER: Sudhir N 

PROVIDER: S-EPMC10404016 | biostudies-literature | 2023 Apr-Jun

REPOSITORIES: biostudies-literature