Measurement of Prevalent Versus Incident Dementia Cases in Epidemiologic Studies.

ABSTRACT: Because dementia is progressive, incident cases are on average milder than prevalent cases, affecting the performance of cognitive tests and questions on functional limitations (i.e., cognition/functional limitation items) used for dementia assessment. Longitudinal studies assess incident cases, while cross-sectional studies assess prevalent cases, but differences are not typically considered when researchers select items to include in studies. We used longitudinal data from the Religious Orders Study and Memory and Aging Project (ROSMAP) (n = 3,446) collected between 1994 and 2021 to characterize differences in associations between items (cognition: 35 items; functional limitations: 14 items) and incident or prevalent dementia using multinomial regression models with generalized estimatin

SUBMITTER: Nichols E 

PROVIDER: S-EPMC10404065 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature