Intestinal microbiome characterization of adult Brazilian men with psoriasis compared to omnivore and vegetarian controls.

ABSTRACT:

Background

Psoriasis is a chronic inflammatory disease associated with systemic inflammation and comorbidities. Changes in the composition of the intestinal microbiome are involved in the pathogenesis of inflammatory diseases and metabolic syndrome. Characterizing the intestinal microbiome of patients with psoriasis may be relevant for the understanding of its clinical course and comorbidity prevention.

Objective

To characterize the intestinal microbiome of men with psoriasis compared to omnivore and vegetarian controls (without psoriasis).

Method

Cross-sectional study of 42 adult males: 21 omnivores with psoriasis; and controls: 14 omnivores and 7 vegetarian individuals. The characterization of the intestinal microbiome was performed by metagenomic analysis. Serum le

SUBMITTER: Polo TCF 

PROVIDER: S-EPMC10404490 | biostudies-literature | 2023 Sep-Oct

REPOSITORIES: biostudies-literature