UniProt and Mass Spectrometry-Based Proteomics-A 2-Way Working Relationship.

ABSTRACT: The human proteome comprises of all of the proteins produced by the sequences translated from the human genome with additional modifications in both sequence and function caused by nonsynonymous variants and posttranslational modifications including cleavage of the initial transcript into smaller peptides and polypeptides. The UniProtKB database (www.uniprot.org) is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information and presents a summary of experimentally verified, or computationally predicted, functional information added by our expert biocuration team for each protein in the proteome. Researchers in the field of mass spectrometry-based proteomics both consume and add to the body of data available in UniProtKB, an

SUBMITTER: Bowler-Barnett EH 

PROVIDER: S-EPMC10404557 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature