Human rotavirus strains circulating among children in the capital of China (2018-2022)_ predominance of G9P[8] and emergence ofG8P[8].

ABSTRACT:

Objective

This study aimed to update the genetic diversity of Rotavirus (RV) infections in children under five years old in Beijing, China.

Methods

A 5-year active hospital-based surveillance for sporadic acute gastroenteritis (AGE) from January 2018 to December 2022 in the capital of China was performed. A total of 748 fecal samples from AGE patients were collected for followed by RV antigen detection by ELSIA, RNA detection by reverse transcription PCR, G/P genotyping and phylogenetic analyzing.

Results

RV antigen was detected in 11.0% of the collected samples, with 54 samples confirmed to be RV RNA positive. G9 and G8 genotypes were identified in 43 (79.6%) and 7 (13.0%) samples, respectively, all of which were allocated to P[8]. The predominant G/P combination was

SUBMITTER: Jiao Y 

PROVIDER: S-EPMC10404872 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature