Liver transplantation for combined hepatocellular carcinoma and cholangiocarcinoma: A multicenter study.

ABSTRACT:

Background

Patients with combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) are not traditionally considered eligible for liver transplantation (LT) due to poor outcomes.

Aim

To compare outcomes between living donor LT (LDLT) patients with hepatocellular carcinoma (HCC) and LT patients with cHCC-CC and to identify risk factors for tumor recurrence and death after LT in cHCC-CC patients.

Methods

Data for pathologically diagnosed cHCC-CC patients (n = 111) who underwent LT from 2000 to 2018 were collected for a nine-center retrospective review. Patients (n = 141) who received LDLT for HCC at Samsung Medical Center from January 2013 to March 2017 were selected as the control group. Seventy patients in two groups, respectively, were selected

SUBMITTER: Kim J 

PROVIDER: S-EPMC10405106 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature