Assessing the Sensitivity of OCT-A Retinal Vasculature Metrics.

ABSTRACT:

Purpose

The purpose of this study was to examine the sensitivity of quantitative metrics of the retinal vasculature derived from optical coherence tomography angiography (OCT-A) images.

Methods

Full retinal vascular slab OCT-A images were obtained from 94 healthy participants. Capillary loss, at 1% increments up to 50%, was simulated by randomly removing capillary segments (1000 iterations of randomized loss for each participant at each percent loss). Thirteen quantitative metrics were calculated for each image: foveal avascular zone (FAZ) area, vessel density, vessel complexity index (VCI), vessel perimeter index (VPI), fractal dimension (FD), and parafoveal intercapillary area (PICA) measurements with and without the FAZ (mean PICA, summed PICA, PICA regularity, and PICA s

SUBMITTER: Szpernal J 

PROVIDER: S-EPMC10405864 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature