A novel biodegradable polymer-coated sirolimus-eluting stent: 1-year results of the HELIOS registry.

ABSTRACT:

Background

The HELIOS stent is a sirolimus-eluting stent with a biodegradable polymer and titanium oxide film as the tie-layer. The study aimed to evaluate the safety and efficacy of HELIOS stent in a real-world setting.

Methods

The HELIOS registry is a prospective, multicenter, cohort study conducted at 38 centers across China between November 2018 and December 2019. A total of 3060 consecutive patients were enrolled after application of minimal inclusion and exclusion criteria. The primary endpoint was target lesion failure (TLF), defined as a composite of cardiac death, non-fatal target vessel myocardial infarction (MI), and clinically indicated target lesion revascularization (TLR) at 1-year follow-up. Kaplan-Meier methods were used to estimate the cumulative incidence o

SUBMITTER: Zheng B 

PROVIDER: S-EPMC10405989 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature