Review: The use of functional magnetic resonance imaging (fMRI) in clinical trials and experimental research studies for depression.

ABSTRACT: Functional magnetic resonance imaging (fMRI) is a non-invasive technique that can be used to examine neural responses with and without the use of a functional task. Indeed, fMRI has been used in clinical trials and pharmacological research studies. In mental health, it has been used to identify brain areas linked to specific symptoms but also has the potential to help identify possible treatment targets. Despite fMRI's many advantages, such findings are rarely the primary outcome measure in clinical trials or research studies. This article reviews fMRI studies in depression that sought to assess the efficacy and mechanism of action of compounds with antidepressant effects. Our search results focused on selective serotonin reuptake inhibitors (SSRIs), the most commonly prescribed treatments

SUBMITTER: Kotoula V 

PROVIDER: S-EPMC10406217 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature