Dependence of resting-state-based cerebrovascular reactivity (CVR) mapping on spatial resolution.

ABSTRACT: Cerebrovascular reactivity (CVR) is typically assessed with a carbon dioxide (CO₂) stimulus combined with BOLD fMRI. Recently, resting-state (RS) BOLD fMRI has been shown capable of generating CVR maps, providing a potential for broader CVR applications in neuroimaging studies. However, prior RS-CVR studies have primarily been performed at a spatial resolution of 3-4 mm voxel sizes. It remains unknown whether RS-CVR can also be obtained at high-resolution without major degradation in image quality. In this study, we investigated RS-CVR mapping based on resting-state BOLD MRI across a range of spatial resolutions in a group of healthy subjects, in an effort to examine the feasibility of RS-CVR measurement at high resolution. Comparing the results of RS-CVR with the maps obtained

SUBMITTER: Liu P 

PROVIDER: S-EPMC10406303 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature