Antimicrobial resistance and clonality of Staphylococcus aureus causing bacteraemia in children admitted to the Manhica District Hospital, Mozambique, over two decades.

ABSTRACT:

Background

Staphylococcus aureus is one of the main causes of bacteraemia, associated with high mortality, mainly due to the occurrence of multidrug resistant (MDR) strains. Data on antibiotic susceptibility and genetic lineages of bacteraemic S. aureus are still scarce in Mozambique. The study aims to describe the antibiotic susceptibility and clonality of S. aureus isolated from blood cultures of children admitted to the Manhiça District Hospital over two decades (2001-2019).

Methods

A total of 336 S. aureus isolates detected in blood cultures of children aged <5 years were analyzed for antibiotic susceptibility by disk diffusion or minimal inhibitory concentration, and for the presence of resistance determinants by PCR. The clonality was evalua

SUBMITTER: Garrine M 

PROVIDER: S-EPMC10406509 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature