Increased hippocampal efficiency is associated with greater headache frequency in adolescents with chronic headache.

ABSTRACT: Adults with chronic headache have altered brain hippocampal efficiency networks. Less is known about the mechanisms underlying chronic headache in youth. In total, 29 youth with chronic headache (10-18 years), and 29 healthy, age- and sex-matched controls tracked their headache attacks daily for 1-month period. Following this, they underwent a resting state functional magnetic resonance imaging scan and self-reported on their pubertal status, post-traumatic stress, anxiety, and depression symptoms. Graph-based topological analyses of brain networks, rendering hippocampal efficiency values were performed. T-tests were used to compare hippocampal efficiency metrics between patients and controls. Linear regression was used to examine significant hippocampal efficiency metrics in relati

SUBMITTER: Cobos KL 

PROVIDER: S-EPMC10406582 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature