Association between serum ALT levels and incidence of new-onset diabetes in general population of Japanese: a longitudinal observational study (ISSA-CKD).

ABSTRACT:

Objective

We aimed to clarify the relationship between serum alanine transaminase (ALT) levels and incidence of new-onset diabetes in a Japanese general population.

Setting

Population-based retrospective cohort study using annual health check-up data for residents of Iki City, Nagasaki Prefecture, Japan.

Participants

A total of 5330 Japanese individuals (≥30 years old) without diabetes at baseline were analysed.

Primary and secondary outcome measures

Serum ALT levels were determined using an enzymatic method and were classified into gender-specific quartile groups as follows: group 1 (3-16 U/L in men and 3-13 U/L in women), group 2 (17-21 U/L in men and 14-16 U/L in women), group 3 (22-29 U/L in men and 17-22 U/L in women) and group 4 (30-428 U/L in men and 23-

SUBMITTER: Morinaga A 

PROVIDER: S-EPMC10407361 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature