Incident dementia in kidney transplantation recipients: a matched comparative nationwide cohort study in South Korea.

ABSTRACT:

Background

Recent studies have shown that patients with end-stage renal disease (ESRD) are at elevated risk of dementia. However, whether kidney transplantation (KT) lowers the risk for incident dementia remains unclear.

Methods

From the Korean National Health Insurance Service database, we identified incident KT recipients aged ≥40 years without any history of dementia between 2007 and 2015. We also established a pair of age-, sex-, and inclusion year-matched control cohorts of patients with incident dialysis-dependent ESRD and members of the general population (GP) without a history of dementia, respectively. Cases of incident all-cause dementia, including Alzheimer disease (AD), vascular dementia (VD), and other kinds of dementia, were obtained from baseline until Decembe

SUBMITTER: Baek SH 

PROVIDER: S-EPMC10407631 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature