Effect of infant viral respiratory disease on childhood asthma in a non-industrialized setting.

ABSTRACT:

Background

There are limited data from non-industrialized settings on the effects of early life viral respiratory disease on childhood respiratory illness. We followed a birth cohort in tropical Ecuador to understand how early viral respiratory disease, in the context of exposures affecting airway inflammation including ascariasis, affect wheezing illness, asthma, and rhinoconjunctivitis in later childhood.

Methods

A surveillance cohort nested within a birth cohort was monitored for respiratory infections during the first 2 years in rural Ecuador and followed for 8 years for the development of wheeze and rhinoconjunctivitis. Nasal swabs were examined for viruses by polymerase chain reaction and respiratory symptom data on recent wheeze and rhinoconjunctivitis were collected

SUBMITTER: Atwell J 

PROVIDER: S-EPMC10408584 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature