Environmental cadmium exposure alters the internal microbiota and metabolome of Sprague-Dawley rats.

ABSTRACT: Cadmium (Cd) is a toxic element that can negatively affect both humans and animals. It enters the human and animal bodies through the respiratory and digestive tracts, following which it tends to accumulate in different organs, thereby seriously affecting human and animal health, as well as hampering social and economic development. Cd exposure can alter the composition of intestinal microbiota. In addition, it can damage the peripheral organs by causing the translocation of intestinal microbiota. However, the relationship between translocation-induced changes in the composition of microbiome in the blood and metabolic changes remains unclear. In the present study, we investigated the effects of Cd exposure on microbiota and serum metabolism in rats by omics analysis. The results demonstra

SUBMITTER: Liu S 

PROVIDER: S-EPMC10410080 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature